Mehta V, Singh S I
Indian J Physiol Pharmacol. 1979 Apr-Jun;23(2):77-85.
Perfusion of the gut lumen with 2 ml of isotonic solutions showed uniform absorption of glucose and water over the four 15-minutes study periods, the absorption being maximum in jejunum and least in colon. With hypertonic solutions the glucose absorption decrease was related to the increasing osmolarity and duration of exposure to the solution as well as the nature of the substance used. Histological changes reflecting impaired functions were localised to the tips of the villi and were observed on exposure to hypertonic solution for 45 minutes or more.
用2毫升等渗溶液灌注肠腔，在四个15分钟的研究期间，葡萄糖和水的吸收是均匀的，空肠吸收最大，结肠吸收最小。使用高渗溶液时，葡萄糖吸收的减少与溶液渗透压的增加、暴露于溶液的持续时间以及所用物质的性质有关。反映功能受损的组织学变化局限于绒毛顶端，在暴露于高渗溶液45分钟或更长时间时观察到。
