Esch W, Loebenstein T
Helv Chir Acta. 1979 Aug;46(3):301-4.
Long-term observations after adrenal surgery show different results according to indications for operations. The longest period of observation shows 8 patients with adrenal hyperplasia. In 3 of 4 bilaterally adrenalectomised patients no satisfactory results were obtained despite substitution treatment; 4 one-side adrenalectomised patients are in good condition. Operative results of 7 patients with benign phaeochromocytoma are satisfactory. Two patients with malignant phaeochromocytoma developed a local recidive and distant metastases. Carcinoma of the adrenal gland, if not hormonally active, were not diagnosed in early stage, 3 patients died from metastases within 3 years. A 2-years-old girl, who was operated on with hormonally active carcinoma, is in good condition 21 years later.
肾上腺手术后的长期观察结果因手术指征而异。观察时间最长的一组中有8例肾上腺增生患者。4例双侧肾上腺切除的患者中,有3例尽管进行了替代治疗,但仍未取得满意效果;4例单侧肾上腺切除的患者情况良好。7例良性嗜铬细胞瘤患者的手术效果令人满意。2例恶性嗜铬细胞瘤患者出现了局部复发和远处转移。肾上腺癌若没有激素活性,则在早期难以诊断,3例患者在3年内死于转移。一名2岁的女孩因激素活性癌接受了手术,21年后情况良好。