Ho S Y, Anderson R H
J Anat. 1979 Jun;128(Pt 4):829-36.
The process of anatomical ductal obliteration appears to be gradual and to involve proliferation of intima and media (mainly the latter) producing mounds, mucoid-filled spaces and fragmentation of the internal elastic membrane. Dissociation of the inner media may also be involved. The persistent ductus can be recognized histologically, and its clinical significance is discussed.
解剖学上导管闭塞的过程似乎是渐进的,涉及内膜和中膜(主要是后者)的增殖,产生隆起、充满黏液的间隙以及内弹性膜的破碎。内膜与中膜的分离也可能参与其中。持续性动脉导管可通过组织学识别,并对其临床意义进行了讨论。