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抗炎药物治疗对类风湿关节炎患者膝关节中¹³³氙清除率的影响。

Effect of anti-inflammatory drug therapy on clearance of 133-Xe from knee joints of patients with rheumatoid arthritis.

作者信息

Dick C, Dick P H, Nuki G, Whaley K, Boyle J A, Shenkin A, Downie W W, Buchanan W W

出版信息

Br Med J. 1969 Aug 2;3(5665):278-80. doi: 10.1136/bmj.3.5665.278.

Abstract

The degree of joint inflammation in 13 patients with rheumatoid arthritis, as measured by clinical indices, was reduced by both sodium salicylate and indomethacin. The clearance rate of (133)Xe was reduced by indomethacin alone, and showed no correlation with the clinical features.

摘要

通过临床指标测量,13例类风湿性关节炎患者的关节炎症程度在使用水杨酸钠和吲哚美辛后均有所减轻。仅吲哚美辛降低了(133)Xe的清除率,且其与临床特征无相关性。

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本文引用的文献

1
Joint temperature measurement in the evaluation of anti-arthritic agents.
J Clin Invest. 1951 Jul;30(7):701-6. doi: 10.1172/JCI102483.
2
MEASUREMENT OF BLOOD-FLOW THROUGH SKELETAL MUSCLE BY INTRAMUSCULAR INJECTION OF XENON-133.
Lancet. 1964 Mar 28;1(7335):686-9. doi: 10.1016/s0140-6736(64)91518-1.
8
Assessment of therapeutic agents in rheumatoid arthritis.
Can Med Assoc J. 1956 Apr 1;74(7):515-21.
9
Phenolsulphonphthalein clearance from the knee joint in normal and pathological states.
Ann Rheum Dis. 1967 May;26(3):246-50. doi: 10.1136/ard.26.3.246.
10
The estimation of inflammatory activity in rheumatoid arthritis. Role of composite indices.
Arthritis Rheum. 1967 Feb;10(1):71-7. doi: 10.1002/art.1780100111.

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