Kones R J, Phillips J H
South Med J. 1976 Apr;69(4):442-8. doi: 10.1097/00007611-197604000-00020.
The course of myocardial necrosis, the clinical syndrome, and methods of treatment are presented. Heart cell death may be prevented by maintaining the balance between myocardial oxygen and energy supply and consumption. New technics of improving this balance by reducing myocardial energy demand, altering metabolism, increasing myocardial substrate supply, and protecting cellular integrity are discussed.
介绍了心肌坏死的病程、临床综合征及治疗方法。通过维持心肌氧供与能量供应和消耗之间的平衡,可预防心脏细胞死亡。讨论了通过降低心肌能量需求、改变代谢、增加心肌底物供应以及保护细胞完整性来改善这种平衡的新技术。