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鱼类心脏中儿茶酚胺释放的液相色谱法证明

Liquid chromatographic demonstration of catecholamine release in fish heart.

作者信息

Cameron J S, O'Connor E F

出版信息

J Exp Zool. 1979 Sep;209(3):473-9. doi: 10.1002/jez.1402090313.

DOI:10.1002/jez.1402090313
PMID:490140
Abstract

High-pressure liquid chromatography (HPLC) was used to assay for catecholamines released into the heart of the goldfish (Carassius auratus L.) upon stimulation of vagal nerve fibers. Stimulation induced the release of norepinephrine, epinephrine and dopamine into the lumen of the perfused, isolated heart. The results suggest that heart activity in teleosts is directly modulated by functional adrenergic, cardioacceleratory nerve fibers.

摘要

采用高压液相色谱法(HPLC)测定刺激金鱼(Carassius auratus L.)迷走神经纤维时释放到其心脏中的儿茶酚胺。刺激可诱导去甲肾上腺素、肾上腺素和多巴胺释放到灌注的离体心脏腔中。结果表明,硬骨鱼类的心脏活动直接受功能性肾上腺素能、心脏加速神经纤维的调节。

相似文献

1
Liquid chromatographic demonstration of catecholamine release in fish heart.鱼类心脏中儿茶酚胺释放的液相色谱法证明
J Exp Zool. 1979 Sep;209(3):473-9. doi: 10.1002/jez.1402090313.
2
Nitric oxide synthase inhibitor inhibits catecholamines release caused by hypogastric sympathetic nerve stimulation.一氧化氮合酶抑制剂可抑制由腹下交感神经刺激引起的儿茶酚胺释放。
J Pharmacol Exp Ther. 1993 Dec;267(3):1363-8.
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Alpha-adrenoceptor mediated facilitation of acetylcholine release in the rat perfused heart.α-肾上腺素能受体介导大鼠离体灌流心脏中乙酰胆碱释放的促进作用。
J Pharmacol Exp Ther. 1990 Aug;254(2):702-10.
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Effects of epinephrine and dopamine on norepinephrine release from the sympathetic nerve endings in hypertension.肾上腺素和多巴胺对高血压患者交感神经末梢去甲肾上腺素释放的影响。
J Hypertens Suppl. 1986 Dec;4(5):S45-8.
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Sympatho-adrenergic activation of the ischemic myocardium and its arrhythmogenic impact.缺血心肌的交感 - 肾上腺素能激活及其致心律失常作用。
Herz. 1995 Jun;20(3):169-86.
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[Study on the catecholamine-containing fibers in the vagus].[迷走神经中含儿茶酚胺纤维的研究]
Nihon Geka Gakkai Zasshi. 1984 Jul;85(7):663-74.
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[Influence of electro-stimulation of central ends of cervical vagi and the right tibial nerve on catecholamine release from the adrenal medulla].[颈迷走神经和右胫神经中枢端电刺激对肾上腺髓质儿茶酚胺释放的影响]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1986 Apr;8(2):121-4.
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Effects of lidocaine on catecholamine release in the ischemic rat heart.
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Dopamine stimulation of cardiac beta-adrenoceptors: the involvement of sympathetic amine transporters and the effect of SKF38393.多巴胺对心脏β-肾上腺素能受体的刺激作用:交感胺转运体的参与及SKF38393的影响
Br J Pharmacol. 1997 Dec;122(8):1669-78. doi: 10.1038/sj.bjp.0701574.
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Optic tectum adenylate cyclase activity from goldfish (Carassius auratus) as a model to assess dopamine receptor agonists and antagonists.以金鱼(Carassius auratus)视顶盖腺苷酸环化酶活性为模型评估多巴胺受体激动剂和拮抗剂。
Res Commun Chem Pathol Pharmacol. 1983 Feb;39(2):241-9.

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