Demeester-Mirkine N, Bossuyt A, Brauman H, Corvilain J
Nouv Presse Med. 1975 Apr 12;4(15):1125-9.
The discovery and the synthesis of the thyrotropin-releasing hormone (T.R.H.) has given rise to a new test able to explore the function of the thyroid and the pituitary. Intravenous injection of T.R.H. determines a short elevation of T.S.H. in the plasma. In hyperthyroidism and in hot nodules the response is abolished. In hypothyroidism, the response depends on the localization of the lesion: exaggerated response in thyroid lesions, diminished or abolished response in pituitary problems, delayed response in hypothalamic lesions. This new test will definitely have an important diagnostic role in difficult clinical problems.
促甲状腺激素释放激素(TRH)的发现与合成催生了一项能够探究甲状腺和垂体功能的新测试。静脉注射TRH可使血浆中促甲状腺激素(TSH)短暂升高。在甲状腺功能亢进和热结节中,这种反应消失。在甲状腺功能减退中,反应取决于病变的部位:甲状腺病变时反应增强,垂体问题时反应减弱或消失,下丘脑病变时反应延迟。这项新测试在疑难临床问题中肯定将发挥重要的诊断作用。