Hsu W T, Weiss S B
Proc Natl Acad Sci U S A. 1969 Sep;64(1):345-51. doi: 10.1073/pnas.64.1.345.
The present studies indicate that T4 infection induces an alteration in host ribosomes which restricts the translation of host and other T4-unrelated template RNAs but permits normal translation of T4 RNA. A heat-labile factor has been isolated from T4-infected cell ribosomes which, when combined with normal cell ribosomes, confers upon the latter the property of selective T4 template RNA translation.
目前的研究表明,T4感染会导致宿主核糖体发生改变,这种改变会限制宿主及其他与T4无关的模板RNA的翻译,但能使T4 RNA正常翻译。已从感染T4的细胞核糖体中分离出一种热不稳定因子,该因子与正常细胞核糖体结合时,会赋予后者选择性翻译T4模板RNA的特性。