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[子宫颈癌的居里疗法。计算机剂量学信息比较。欧洲居里治疗师小组合作研究(作者译)]

[Curietherapy in the carcinoma of the uterine cervix. Comparison of the obtained by computer dosimetric informations. Cooperative study by the European Group of curietherapists (author's transl)].

出版信息

J Radiol. 1979 May;60(5):361-70.

PMID:490487
Abstract

A cooperative study was taken to comparate the doses, obtained by the different institutes. The European Group had first defined the important points of the irradiated volume. This study has shown the great differencies between the doses of the institutes. First, the reference points for the surrounding structures were examined. The average of the doses at the inferior points of the Fletcher's lymphatic trapezium varies between 500 and 1 500 rads. This at the pelvic wall point is usually more important (10 or 15%). The doses at the delicate organs, the bladder and the rectum were studied in second. The average of the maximal vesical doses varies from 4 000 to 4 900 rads in the preoperative group; the average of the maximal rectal doses between 2 100 and 5 200 rads in the same group. The examination of the mean rectal dose was difficult. Every Institute has his own means of determining it. At last the size of the reference volume was considered. The 6 000 rads isodose was selected for the whole treatment. The height of this volume seems to be essentially dependent of the length of the uterine source. There seems existing some parallelism between the width and the thickness of the reference volume, but there are many differencies from an Institute to another. Now the Group has to determine a dosimetric methodology which may be transmissible.

摘要

开展了一项合作研究,以比较不同机构获得的剂量。欧洲研究小组首先确定了照射体积的要点。这项研究显示了各机构之间剂量的巨大差异。首先,检查了周围结构的参考点。弗莱彻淋巴梯形下部各点的平均剂量在500至1500拉德之间变化。骨盆壁点的剂量通常更高(10%或15%)。其次研究了膀胱和直肠等敏感器官的剂量。术前组最大膀胱剂量的平均值在4000至4900拉德之间;同一组中最大直肠剂量的平均值在2100至5200拉德之间。平均直肠剂量的测定很困难。每个机构都有自己的测定方法。最后考虑了参考体积的大小。整个治疗选择6000拉德等剂量线。该体积的高度似乎主要取决于子宫源的长度。参考体积的宽度和厚度之间似乎存在一定的平行关系,但不同机构之间存在许多差异。现在该小组必须确定一种可传播的剂量测定方法。

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