Malinowski R W, Strate R G, Perry J F, Fischer R P
J Trauma. 1979 Sep;19(9):655-9. doi: 10.1097/00005373-197909000-00003.
Three hundred twenty-seven bite injuries of the hand were reviewed for incidence of infectious complications. A policy to hospitalize all patients with human bite injuries was maintained, but noncompliance was high. Patients with uninfected or superficially infected bites (131) were hospitalized and treated with parenteral penicillin, cephalosporins, or clindamycin (mean duration, 45 hours). Among the 62 patients not lost to followup three minor septic complications occurred. Of similar patients not hospitalized (134), only two thirds received antibiotic therapy but no complications were observed. These data suggest that human bite hand infections can be averted and that established superficial infections can be successfully treated with outpatient antibiotic therapy. Of the 62 patients with moderately to severely infected human bites, 77% were injured by striking an opponent; 52% suffered injury over metacarpophalangeal joints. The mean delay in seeking medical attention was 2 1/2 days, compared to 1/2 day in the less severely infected group. Of the patients with more seriously infected bites, 94% received parenteral antibiotic therapy. Of 30 patients with known outcome in the latter group 27% suffered complications (stiffness; recurrent infection; other infectious complication), confirming the high morbidity of established deep hand infections secondary to human bites.
对327例手部咬伤进行回顾性研究,以确定感染并发症的发生率。我们坚持对所有人类咬伤患者进行住院治疗的政策,但不遵守规定的情况很严重。未感染或轻度感染咬伤的患者(131例)住院治疗,接受胃肠外青霉素、头孢菌素或克林霉素治疗(平均疗程45小时)。在62例未失访的患者中,发生了3例轻度败血症并发症。在未住院治疗的类似患者(134例)中,只有三分之二接受了抗生素治疗,但未观察到并发症。这些数据表明,人类咬伤手部感染是可以避免的,已确诊的轻度感染可以通过门诊抗生素治疗成功治愈。在62例中度至重度感染的人类咬伤患者中,77%是在与对手搏斗时受伤;52%的损伤发生在掌指关节处。寻求医疗帮助的平均延迟时间为2.5天,而轻度感染组为0.5天。在咬伤感染较严重的患者中,94%接受了胃肠外抗生素治疗。在后一组已知结局的30例患者中,27%发生了并发症(僵硬;反复感染;其他感染并发症),证实了人类咬伤继发的严重手部深部感染的高发病率。