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[院外猝死的病理学。1. 冠状动脉阻塞性病变及心肌瘢痕]

[Pathology of sudden extra-hospital death. 1. Obstructive lesions of the coronary arteries and myocardial scars].

作者信息

Ianushkevichus Z I, Stalioraĭtite E I, Bluzhas Iu N, Cheponus I I, Rizhakovaĭte M V

出版信息

Kardiologiia. 1979 Aug;19(8):23-7.

PMID:491353
Abstract

The coronary arteries and myocardium were examined morphologically by special unified methods in 127 cases of prehospital sudden coronary death among Kaunas male population from 45 to 65 years of age. Obstruction of at least one of four major coronary arteries was severe (75% or more) in 90% of patients and moderate (50--75%) in the remaining 10%. In most cases one or two coronary arteries had severe obstruction (77% of cases) located predominantly in the proximal and middle segments of the left anterior descending and right coronary arteries. Post-infarction scars and small foci of myocardial sclerosis were found in 72% of hearts any may be considered as special "morphological catamnesis" of past acute coronary events. In 85% of cases the heart mass was more than 400 g. The data presented indicate the undoubted role of coronarogenic factors in the development of an acute terminal episode such as sudden death, the unexpectedness of which is only imaginary.

摘要

采用特殊统一方法,对考纳斯市45至65岁男性人群中127例院前冠状动脉猝死病例的冠状动脉和心肌进行了形态学检查。90%的患者至少有一条主要冠状动脉严重阻塞(75%或以上),其余10%为中度阻塞(50%-75%)。在大多数情况下,一或两条冠状动脉严重阻塞(占病例的77%),主要位于左前降支和右冠状动脉的近端和中段。72%的心脏发现有心肌梗死后瘢痕和心肌硬化小病灶,可视为过去急性冠状动脉事件的特殊“形态学转归”。85%的病例心脏重量超过400克。所提供的数据表明,冠状动脉源性因素在诸如猝死这种急性终末事件的发生中具有毋庸置疑的作用,而猝死的意外性只是假象。

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