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[院外猝死的病理学。1. 冠状动脉阻塞性病变及心肌瘢痕]

[Pathology of sudden extra-hospital death. 1. Obstructive lesions of the coronary arteries and myocardial scars].

作者信息

Ianushkevichus Z I, Stalioraĭtite E I, Bluzhas Iu N, Cheponus I I, Rizhakovaĭte M V

出版信息

Kardiologiia. 1979 Aug;19(8):23-7.

PMID:491353
Abstract

The coronary arteries and myocardium were examined morphologically by special unified methods in 127 cases of prehospital sudden coronary death among Kaunas male population from 45 to 65 years of age. Obstruction of at least one of four major coronary arteries was severe (75% or more) in 90% of patients and moderate (50--75%) in the remaining 10%. In most cases one or two coronary arteries had severe obstruction (77% of cases) located predominantly in the proximal and middle segments of the left anterior descending and right coronary arteries. Post-infarction scars and small foci of myocardial sclerosis were found in 72% of hearts any may be considered as special "morphological catamnesis" of past acute coronary events. In 85% of cases the heart mass was more than 400 g. The data presented indicate the undoubted role of coronarogenic factors in the development of an acute terminal episode such as sudden death, the unexpectedness of which is only imaginary.

摘要

采用特殊统一方法,对考纳斯市45至65岁男性人群中127例院前冠状动脉猝死病例的冠状动脉和心肌进行了形态学检查。90%的患者至少有一条主要冠状动脉严重阻塞(75%或以上),其余10%为中度阻塞(50%-75%)。在大多数情况下,一或两条冠状动脉严重阻塞(占病例的77%),主要位于左前降支和右冠状动脉的近端和中段。72%的心脏发现有心肌梗死后瘢痕和心肌硬化小病灶,可视为过去急性冠状动脉事件的特殊“形态学转归”。85%的病例心脏重量超过400克。所提供的数据表明,冠状动脉源性因素在诸如猝死这种急性终末事件的发生中具有毋庸置疑的作用,而猝死的意外性只是假象。

相似文献

1
[Pathology of sudden extra-hospital death. 1. Obstructive lesions of the coronary arteries and myocardial scars].[院外猝死的病理学。1. 冠状动脉阻塞性病变及心肌瘢痕]
Kardiologiia. 1979 Aug;19(8):23-7.
2
[Atherosclerotic stenosis of the coronary arteries and contraction lesions of the myocardium in sudden coronary death].[冠状动脉粥样硬化性狭窄与心源性猝死中心肌的收缩性病变]
Arkh Patol. 1985;47(3):14-9.
3
Quantitation of coronary arterial narrowing at necropsy in sudden coronary death: analysis of 31 patients and comparison with 25 control subjects.心脏性猝死尸检时冠状动脉狭窄的定量分析:31例患者分析及与25例对照者的比较
Am J Cardiol. 1979 Jul;44(1):39-45. doi: 10.1016/0002-9149(79)90248-0.
4
[Sudden death outside the hospital from coronary heart disease: the state of the intercoronary artery collaterals].[院外冠心病猝死:冠状动脉间侧支循环状态]
Arkh Patol. 1985;47(4):22-6.
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Sudden out-of-hospital coronary death and chronic lesions of coronary arteries and myocardium: morphologic data of Kaunas male population study.院外突发冠心病死亡与冠状动脉及心肌的慢性病变:考纳斯男性人群研究的形态学数据
Acta Med Scand Suppl. 1978;615:33-40. doi: 10.1111/j.0954-6820.1978.tb17496.x.
6
[Relationship of focal lesions in the myocardium to coronary arteriosclerosis in sudden death].[心肌局灶性病变与猝死中冠状动脉粥样硬化的关系]
Arkh Patol. 1979;41(2):10-5.
7
[Changes in the angioarchitectonics of the heart in sudden coronary death].[猝死时心脏血管构筑学的变化]
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8
Nonobstructive coronary thrombosis in sudden cardiac death.心脏性猝死中的非阻塞性冠状动脉血栓形成。
Am J Cardiol. 1978 Jul;42(1):48-51. doi: 10.1016/0002-9149(78)90983-9.
9
Sudden coronary death: comparison of patients with to those without coronary thrombus at necropsy.心脏性猝死:尸检时伴有与不伴有冠状动脉血栓形成的患者对比。
Am J Cardiol. 1984 Dec 1;54(10):1206-11. doi: 10.1016/s0002-9149(84)80068-5.
10
Sudden coronary death: relation of amount and distribution of coronary narrowing at necropsy to previous symptoms of myocardial ischemia, left ventricular scarring and heart weight.心脏性猝死:尸检时冠状动脉狭窄的程度和分布与心肌缺血既往症状、左心室瘢痕形成及心脏重量的关系。
Am J Cardiol. 1984 Jul 1;54(1):65-73. doi: 10.1016/0002-9149(84)90305-9.