Human ecological cardiology studies the interaction of the cardiovascular system and its regulating apparatus with the natural environment to clarify their morpho-functional formation, the mechanisms of the development of disorders and their adequate correction and the use of this natural environment for therapeutic and prophylactic purposes. Problems of adaptation of the cardiovascular system to extreme environmental conditions (high-altitude hypoxia) are discussed. Four groups of trace reactions in adaptation to the environment are described. High-altitude pathology of the cardiovascular system is systemized.