Bukauskas F F
Kardiologiia. 1979 Sep;19(9):95-9.
The results of studying the electrophysiological parameters on the boundary between the normal and the hypoxic area of the myocardium are discussed. The experiments were conducted on isolated preparation of the rabbit atrium with the use of microelectrodes for recording the transmembrane action potentials. The existence of the "maintenance" effect is shown, which is manifested by the better survival of the hypoxic area located nearer to the transitional zone as compared to the survival of a more distant area. The "maintenance" effect is due to the electrotonic interrelationship and to the intercellular diffuse processes of the ions and metabolites. With the continuation of the effect of hypoxia, the transitional zone becomes narrower, one of the causes of which is the disturbed intercellular relationship.
讨论了对心肌正常区域与缺氧区域边界处电生理参数进行研究的结果。实验采用微电极记录跨膜动作电位,在兔心房离体标本上进行。结果显示存在“维持”效应,即与距离较远的缺氧区域相比,靠近过渡区的缺氧区域存活情况更好。“维持”效应归因于电紧张相互关系以及离子和代谢产物的细胞间扩散过程。随着缺氧效应的持续,过渡区变窄,其原因之一是细胞间关系受到干扰。