Laitinen L V
J Neurol Neurosurg Psychiatry. 1970 Aug;33(4):513-8. doi: 10.1136/jnnp.33.4.513.
Stereotaxic subthalamotomy of 55 patients with cerebral palsy gave a good result in 65% of the selected cases. The result was uncertain in 15 and poor in 20%. An independent socio-medical follow-up study confirmed the clinical finding. The more rapid the involuntary movements, the better was the effect of subthalamotomy. Intention tremor was the most suitable symptom for stereotaxic treatment. Rigidospasticity was alleviated in the distal muscles only. Speech and gait were often improved. Good results were obtained in patients with normal intelligence, while feeble-minded patients did not benefit from the operation. Subthalamotomy was followed by transitory side-effects in 20%, of which increased involuntary movements on the ipsilateral side and mental restlessness were the most frequent. The operation had no mortality. Spinal longitudinal myelotomy effectively relieved the spasticity of the lower limbs in the three patients operated upon.
对55例脑瘫患者进行立体定向丘脑底核毁损术,在所选病例中65%效果良好。15%的结果不确定,20%效果差。一项独立的社会医学随访研究证实了临床发现。不自主运动越快,丘脑底核毁损术的效果越好。意向性震颤是立体定向治疗最合适的症状。仅远端肌肉的强直痉挛得到缓解。言语和步态常有所改善。智力正常的患者效果良好,而弱智患者手术无获益。20%的患者术后出现短暂副作用,其中同侧不自主运动增加和精神烦躁最为常见。该手术无死亡病例。脊髓纵切术有效缓解了3例接受手术患者下肢的痉挛。