人类骨骼肌中的圆柱形螺旋结构。

Cylindrical spirals in human skeletal muscle.

作者信息

Carpenter S, Karpati G, Robitaille Y, Melmed C

出版信息

Muscle Nerve. 1979 Jul-Aug;2(4):282-7. doi: 10.1002/mus.880020407.

DOI:10.1002/mus.880020407

Abstract

Muscle biopsies from two patients revealed that numerous type 2 fibers contained large abnormal areas filled with cylindrical spirals. The cytochemical profile of these cylindrical spirals was sufficiently characteristic that they could be distinguished from tubular aggregates. Their electron microscopic appearance was unmistakable. Their origin and significance are uncertain. The diverse nature of the patients' conditions (cramps and malignancy, and an unusual form of spinocerebellar degeneration) indicate that these abnormal structures are not disease specific.

摘要

两名患者的肌肉活检显示，许多2型纤维含有大量充满圆柱形螺旋体的异常区域。这些圆柱形螺旋体的细胞化学特征具有足够的特异性，使其能够与管状聚集物区分开来。它们的电子显微镜外观是明确无误的。它们的起源和意义尚不确定。患者病情的多样性（痉挛、恶性肿瘤以及一种不寻常形式的脊髓小脑变性）表明，这些异常结构并非疾病特异性的。