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人类骨骼肌中的圆柱形螺旋结构。

Cylindrical spirals in human skeletal muscle.

作者信息

Carpenter S, Karpati G, Robitaille Y, Melmed C

出版信息

Muscle Nerve. 1979 Jul-Aug;2(4):282-7. doi: 10.1002/mus.880020407.

DOI:10.1002/mus.880020407
PMID:492204
Abstract

Muscle biopsies from two patients revealed that numerous type 2 fibers contained large abnormal areas filled with cylindrical spirals. The cytochemical profile of these cylindrical spirals was sufficiently characteristic that they could be distinguished from tubular aggregates. Their electron microscopic appearance was unmistakable. Their origin and significance are uncertain. The diverse nature of the patients' conditions (cramps and malignancy, and an unusual form of spinocerebellar degeneration) indicate that these abnormal structures are not disease specific.

摘要

两名患者的肌肉活检显示,许多2型纤维含有大量充满圆柱形螺旋体的异常区域。这些圆柱形螺旋体的细胞化学特征具有足够的特异性,使其能够与管状聚集物区分开来。它们的电子显微镜外观是明确无误的。它们的起源和意义尚不确定。患者病情的多样性(痉挛、恶性肿瘤以及一种不寻常形式的脊髓小脑变性)表明,这些异常结构并非疾病特异性的。

相似文献

1
Cylindrical spirals in human skeletal muscle.人类骨骼肌中的圆柱形螺旋结构。
Muscle Nerve. 1979 Jul-Aug;2(4):282-7. doi: 10.1002/mus.880020407.
2
Cylindrical spirals in skeletal muscle: a further observation with clinical, morphological, and biochemical analysis.骨骼肌中的圆柱形螺旋:临床、形态学及生化分析的进一步观察
Muscle Nerve. 1983 Nov-Dec;6(9):646-55. doi: 10.1002/mus.880060905.
3
Muscle pain associated with tubular aggregates and structures resembling cylindrical spirals.与管状聚集体及类似圆柱形螺旋结构相关的肌肉疼痛。
Muscle Nerve. 1989 Apr;12(4):265-72. doi: 10.1002/mus.880120403.
4
[A case of progressive myopathy with tubular aggregates].
Rinsho Shinkeigaku. 1989 Jun;29(6):769-73.
5
Type 2 fiber predominance in muscle cramp and exertional myalgia.2型纤维在肌肉痉挛和运动性肌痛中占优势。
Muscle Nerve. 1985 Sep;8(7):563-7. doi: 10.1002/mus.880080704.
6
[5 cases of stress myalgia with tubular aggregates].5例伴有管状聚集物的应激性肌痛
Rev Rhum Mal Osteoartic. 1990 Apr 25;57(4):299-301.
7
[Familial myopathy associated with tubular aggregates--report of two siblings].[与管状聚集物相关的家族性肌病——两例同胞病例报告]
Rinsho Shinkeigaku. 1995 Sep;35(9):1016-20.
8
Cramps, muscle pain, and tubular aggregates.痉挛、肌肉疼痛和管状聚集物。
Arch Neurol. 1980 Nov;37(11):715-7. doi: 10.1001/archneur.1980.00500600063013.
9
Two types of mitochondrial crystals in diseased human skeletal muscle fibers.
Muscle Nerve. 1988 Jan;11(1):45-55. doi: 10.1002/mus.880110109.
10
[Enzyme histochemistry in the biopsy diagnosis of skeletal muscle diseases].[酶组织化学在骨骼肌疾病活检诊断中的应用]
Acta Histochem Suppl. 1983;28:75-84.

引用本文的文献

1
Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness.包涵体肌病 3 突变表达在果蝇中抑制肌球蛋白功能和稳定性,并重现肌肉包涵体和肌无力。
Mol Biol Cell. 2012 Jun;23(11):2057-65. doi: 10.1091/mbc.E12-02-0120. Epub 2012 Apr 11.
2
High serum creatine kinase levels associated with cylindrical spirals at muscle biopsy.
Acta Neuropathol. 1995;90(6):660-4. doi: 10.1007/BF00318582.
3
Tubular aggregates: their association with myalgia.管状聚集物:它们与肌痛的关联。
J Neurol Neurosurg Psychiatry. 1985 Sep;48(9):882-6. doi: 10.1136/jnnp.48.9.882.