DeCherney A, Kase N
Obstet Gynecol. 1979 Oct;54(4):451-5.
With the earlier and more accurate diagnosis of ectopic pregnancy based on rapid beta-subunit pregnancy tests and the use of ultrasound and laparoscopy, the percentage of diagnosed unruptured ectopic pregnancies is rapidly increasing. This, coupled with the earlier treatment of pelvic inflammatory disease, the use of IUDs, and increasing numbers of tubal plastic surgery, caused the authors to evaluate the problem of conservative management of ectopic pregnancy. In this study 98 patients at the Yale-New Haven Hospital who had ectopic pregnancies between 1972 and 1977 are evaluated. Fifty of these patients underwent a salpingectomy or salpingo-oophorectomy. Forty-eight patients underwent salpingostomy. This represents an increase in the conservative surgery rate from 8 to 35.5%. The overall term viable pregnancy rate was 40%, along with a 10% repeat ectopic rate. There was no advantage as far as term viable pregnancy when comparing salpingostomy and salpingectomy. Conservative surgery did not increase the repeat ectopic rate. Salpingostomy is therefore recommended in unruptured ampullar ectopic pregnancies in order to preserve reproductive function. If current trends continue, this will be an increasingly important problem. The statistics are based on a 73% follow-up, with all patients actively trying to conceive.
基于快速β亚基妊娠试验以及超声和腹腔镜检查技术,异位妊娠的诊断得以更早期、更准确,从而使已诊断出的未破裂异位妊娠的比例迅速上升。这一情况,再加上盆腔炎治疗的早期化、宫内节育器的使用以及输卵管整形手术数量的增加,促使作者对异位妊娠的保守治疗问题进行评估。在本研究中,对1972年至1977年间在耶鲁 - 纽黑文医院发生异位妊娠的98例患者进行了评估。其中50例患者接受了输卵管切除术或输卵管卵巢切除术。48例患者接受了输卵管造口术。这表明保守手术率从8%提高到了35.5%。足月活产妊娠率总体为40%,重复异位妊娠率为10%。比较输卵管造口术和输卵管切除术后,在足月活产妊娠方面并无优势。保守手术并未增加重复异位妊娠率。因此,对于未破裂的壶腹部异位妊娠,建议采用输卵管造口术以保留生殖功能。如果当前趋势持续下去,这将成为一个日益重要的问题。这些统计数据基于73%的随访率,所有患者均积极尝试受孕。