氢溴酸非那佐辛（Narphen）与硫酸吗啡对急性腹痛患者镇痛效果的双盲临床试验。
Double-blind clinical trial of the analgesic effects of phenazocine hydrobromide (Narphen) compared with morphine sulphate in patients with acute abdominal pain.
作者信息
Hopton D
出版信息
Gut. 1971 Jan;12(1):51-4. doi: 10.1136/gut.12.1.51.
Abstract
No significant difference could be detected either by clinical impression or statistical analysis in the relief of pain afforded by 2.5 mg phenazocine hydrobromide (Narphen) and 10 mg morphine sulphate when given by intramuscular injection to patients with acute abdominal pain. Phenazocine does not cause spasm of the sphincter of Oddi and so is recommended for treating biliary or pancreatic pain.
摘要
对急性腹痛患者肌内注射2.5毫克氢溴酸非那佐辛（纳芬）和10毫克硫酸吗啡后，无论是临床印象还是统计分析，都未发现二者在缓解疼痛方面有显著差异。非那佐辛不会引起Oddi括约肌痉挛，因此推荐用于治疗胆源性或胰腺性疼痛。
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本文引用的文献
1
A clinical comparison of two new narcotic analgesics.
Curr Ther Res Clin Exp. 1959 Dec;1:109-14.
2
The use of phenazocine (prinadol) in surgical patients.
Surg Gynecol Obstet. 1960 Jun;110:669-72.
3
The clinical measurement of pain.
Ann N Y Acad Sci. 1960 Mar 30;86:28-37. doi: 10.1111/j.1749-6632.1960.tb42788.x.
4
A COMPARISON OF MORPHINE AND PHENAZOCINE IN POSTOPERATIVE PAIN.
Br J Anaesth. 1964 Dec;36:782-6. doi: 10.1093/bja/36.12.782.
5
Action of various new analgesic drugs on the human common bile duct.
Gut. 1967 Jun;8(3):296-300. doi: 10.1136/gut.8.3.296.
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