Bourgeon R, Isman H, Brisard M
Nouv Presse Med. 1979 Jun 16;8(27):2273-8.
Statistical results show a marked improvement in survival after surgical treatment of hepatic metastases. The possibilities of surgery are evaluated after precise analysis of the lesions seen at the time of excision and not at autopsy. The data from assessment which indicate that surgery will be successful are described and discussed. Surgical techniques consist above all of resection: metastasectomy, segmentectomy, hemihepatectomy and hepatectomy followed by transplant. Other methods are palliative. Certain resections themselves appear to be palliative and the ideal is to carry out adequate resection at the outset, adapted to the size and site of the lesions. However the possibilities of surgery form part of an overall programme: -- complete removal of the primary carcinoma in order to avoid any local recurrence, -- wide eradication of metastatic lesions, -- préventive treatment against further development of possible subclinical lesions by post-surgical chemotherapy and subsequent immunotherapy.
统计结果显示，肝转移瘤手术治疗后的生存率有显著提高。手术可能性是在切除时（而非尸检时）对所见病灶进行精确分析后评估的。描述并讨论了表明手术将会成功的评估数据。手术技术首先包括切除：转移瘤切除术、肝段切除术、半肝切除术和肝切除术后移植。其他方法是姑息性的。某些切除术本身似乎就是姑息性的，理想情况是一开始就进行充分的切除，使其适应病灶的大小和部位。然而，手术可能性是整个治疗方案的一部分：—— 完全切除原发性癌以避免任何局部复发，—— 广泛根除转移病灶，—— 通过术后化疗及后续免疫疗法对可能的亚临床病灶的进一步发展进行预防性治疗。
