伯明翰医学研究探险协会1977年探险：徒步前往高海拔地区期间的利尿及相关变化。
Birmingham Medical Research Expeditionary Society 1977 Expedition: the diuresis and related changes during a trek to high altitude.
作者信息
Howell A, Cove D H
出版信息
Postgrad Med J. 1979 Jul;55(645):471-4. doi: 10.1136/pgmj.55.645.471.
Abstract
Continuous 24-hr urine collections were made by 17 subjects during a trek to 5400 m. Fluid intake was recorded by diary. Weight and fat folds were measured daily. The results were compared with daily measurements of packed cell volume (PCV) and reticulocyte count. Early fluid retention was matched by a fall in PCV. There was a diuresis with negative fluid balance towards the end of the ascent and again early in descent. There was a slight trend for fluid retention to occur in those most affected by acute mountain sickness but the effect was not marked.
摘要
17名受试者在徒步前往5400米高度的过程中进行了24小时连续尿液收集。通过日记记录液体摄入量。每天测量体重和脂肪褶厚度。将结果与每日测得的红细胞压积（PCV）和网织红细胞计数进行比较。早期液体潴留与PCV下降相匹配。在上升接近尾声时以及下降初期出现了利尿和负水平衡。在受急性高山病影响最严重的人群中，有轻微的液体潴留趋势，但影响并不显著。
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