Merlen J F, Coget J, Sarteel A M
Phlebologie. 1979 Jul-Sep;32(3):303-7.
Following a nosological discussion of the varicose vein, its histological, biochemical and immunological elements are detailed. The hydraulic conditions are described, and attention is drawn to the microvasculartissue consequences of the stasis, the degree of constraint exercised by the interstitial tissue, and the role played by the intricate "micro fiber" network of the microcirculation: only a part of the capillaries reconnect with the veinlet of the same circulatory unit, the others having to flow toward the veinlet of other units and only one initial lymphatic vein contributing to the evacuation of 3 to 4 veinlets. The slightest hydraulic imbalance due to the stasis, sets of a whole series of chain reactions that can rapidly become harmful, with chronic veinous deficiency setting in.
在对静脉曲张进行疾病分类学讨论之后，详细阐述了其组织学、生物化学和免疫学要素。描述了水力条件，并提请注意淤血对微血管组织的影响、间质组织施加的约束程度以及微循环中复杂“微纤维”网络所起的作用：只有一部分毛细血管与同一循环单元的小静脉重新连接，其他的则必须流向其他单元的小静脉，并且只有一条初始淋巴管负责3至4条小静脉的引流。由于淤血导致的最轻微的水力失衡都会引发一系列连锁反应，这些反应可能会迅速变得有害，进而导致慢性静脉功能不全。
