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[使用纤维蛋白原底物对炎症改变和人工血染脑脊液进行血栓弹力图和免疫纤维蛋白溶解测定]

[Thromboelastographic and immunologic fibrinolysis determinations in inflammatory-changed and artificial blood stained cerebrospinal fluids using fibrinogen substrate].

作者信息

Hindersin P, Heidrich R

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1979 Apr;31(4):197-202.

PMID:493425
Abstract

In in-vitro long-term tests, the free fibrinolytic activity was determined from inflammatory-changed and blood stained cerebrospinal fluids in which partly fibrinogen concentrations insufficient for the enzyme-catalysed fibrinolytic reaction were present, using after addition of substrate (fibrinogen, plasma) thrombelastography and fibrin degradation products (FDP) recording. The results confirm a free fibrinolytic activity in many inflammatory-changed and blood stained cerebrospinal fluids. The difference in the results obtained with reaction preparations with substrate and those with too low fibrinogen concentrations are discussed.

摘要

在体外长期试验中,针对炎症改变且带血的脑脊液测定其游离纤溶活性,这些脑脊液中部分纤维蛋白原浓度不足以支持酶催化的纤溶反应,方法是在添加底物(纤维蛋白原、血浆)后使用血栓弹力图和记录纤维蛋白降解产物(FDP)。结果证实许多炎症改变且带血的脑脊液存在游离纤溶活性。讨论了使用含底物的反应制剂与纤维蛋白原浓度过低的制剂所获得结果的差异。

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