吗啡、纳洛酮和 kainic 酸神经毒性。（注：kainic acid 一般译为“ kainic 酸” 或“海人藻酸”，具体可视语境选择更合适的表达。这里直接按要求保留英文原名。）

Morphine, naloxone and kainic acid neurotoxicity.

作者信息

McGeer E G, McGeer P L, Vincent S R

出版信息

Res Commun Chem Pathol Pharmacol. 1979 Aug;25(2):411-4.

Abstract

Local neuronal damage, as indicated by choline acetyltransferase and glutamate decarboxylase activities, elicited by intrastriatal injections of kainic acid was increased by local injection of morphine and decreased by prior injection of naloxone. Peripheral injections of morphine or naloxone had little significant effect although the same trends appeared.

摘要

如通过胆碱乙酰转移酶和谷氨酸脱羧酶活性所表明的那样，纹状体内注射红藻氨酸引发的局部神经元损伤，会因局部注射吗啡而增加，并因预先注射纳洛酮而减少。尽管出现了相同的趋势，但吗啡或纳洛酮的外周注射几乎没有显著影响。