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拟除虫菊酯的结构与活性之间的关系。

The relationship between the structure and the activity of pyrethroids.

作者信息

Elliott M

出版信息

Bull World Health Organ. 1971;44(1-3):315-24.

Abstract

There is considerable scope for developing new non-persistent insecticides with little hazard for man and mammals by modifying the structures of the natural pyrethrins. New compounds already synthesized are more effective against some insect species than are the natural compounds, are even less hazardous to mammals, and do not need synergists to supplement their insecticidal action. Other examples show considerable insect species specificity. These compounds may help to control insect vectors when other insecticides are no longer effective because resistance has developed or because their residues can no longer be tolerated.

摘要

通过改变天然除虫菊酯的结构来开发对人类和哺乳动物危害极小的新型非持久性杀虫剂,有很大的空间。已经合成的新化合物对某些昆虫种类比天然化合物更有效,对哺乳动物的危害甚至更小,并且不需要增效剂来补充其杀虫作用。其他例子显示出相当大的昆虫种类特异性。当其他杀虫剂由于产生抗药性或因其残留不再被容忍而不再有效时,这些化合物可能有助于控制昆虫媒介。

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本文引用的文献

1
Chemistry of the natural pyrethrins.
Fortschr Chem Org Naturst. 1961;19:120-64. doi: 10.1007/978-3-7091-7156-1_3.
2
New pyrethrin-like esters with high insecticidal activity.
Nature. 1965 Aug 28;207(5000):938-40. doi: 10.1038/207938a0.
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Mixed-function oxidase involvement in the biochemistry of insecticide synergists.
J Agric Food Chem. 1970 Sep-Oct;18(5):753-72. doi: 10.1021/jf60171a013.

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