Andersson H, Fasth S, Filipsson S, Hellberg R, Hultén L, Nilsson L O, Nordgren S, Kock N G
Scand J Gastroenterol. 1979;14(5):551-4. doi: 10.3109/00365527909181388.
Bile salt absorption, as determined by the faecal excretion in i.v. injected 14C-cholic acid (FBS) was studied in 13 ileostomy patients before and after conversion to Kock's continent ileostomy reservoir. The result was compared with that obtained in 8 ileostomy patients in whom about 50 cm of the terminal ileum has also been removed. As compared with 16 healthy controls, FBS was moderately increased in the conventional ileostomy patients, but still within normal limits. After conversion to ileostomy reservoir all patients had pathological FBS, although less severe than in the ileostomy patients with ileal resection. Bacterial contamination probably contributes more than the structural mucosal changes to the bile malabsorption in the pouch, whereas reduced mucosal surface and short small-intestinal transit time are the main causes of malabsorption in ileostomy patients in whom an appreciable amount of the terminal ileum has been resected.
通过静脉注射14C - 胆酸后的粪便排泄量来测定胆汁盐吸收情况（FBS），对13例回肠造口术患者在转换为科克可控回肠造口袋之前和之后进行了研究。将结果与8例也切除了约50 cm末段回肠的回肠造口术患者的结果进行比较。与16名健康对照者相比，传统回肠造口术患者的FBS适度增加，但仍在正常范围内。转换为回肠造口袋后，所有患者的FBS均呈病理性，尽管不如回肠切除的回肠造口术患者严重。细菌污染可能比黏膜结构改变对袋囊中胆汁吸收不良的影响更大，而黏膜表面积减少和小肠转运时间缩短是切除了相当长度末段回肠的回肠造口术患者吸收不良的主要原因。
