Schjonsby H, Halvorsen J F, Hofstad T, Hovdenak N
Gut. 1977 Oct;18(10):795-9. doi: 10.1136/gut.18.10.795.
Intestinal absorption and bacteriology of the ileal contents were compared in seven patients with continent ileostomy and seven patients with conventional ileostomy. The absorption of vitamin B12 was reduced in five patients with continent ileostomy and subnormal in two patients with conventional ileostomy. Steatorrhoea was present in four patients with continent and one patient with conventional ileostomy. Increased concentrations of total anaerobic bacteria and Bacteroides were found in the ileum of the patients with continent ileostomy. After an oral dose of (1-14C) glycocholic acid there was no difference in the faecal excretion of radioactivity, whereas the 14CO2-expiration was increased in two patients with continent ileostomy. In four patients with continent ileostomy and malabsorption of B12, there was evidence of a stagnant loopsyndrome as oral lincomycin treatment resulted in increased absorption of B12 decreased excretion of faecal fat, and decreased concentrations of Bacteroides in the ileum.
对7例可控性回肠造口术患者和7例传统回肠造口术患者的回肠内容物的肠道吸收和细菌学进行了比较。5例可控性回肠造口术患者的维生素B12吸收减少,2例传统回肠造口术患者的维生素B12吸收低于正常水平。4例可控性回肠造口术患者和1例传统回肠造口术患者出现脂肪泻。在可控性回肠造口术患者的回肠中发现总厌氧菌和拟杆菌的浓度增加。口服(1-14C)甘氨胆酸后,粪便放射性排泄物没有差异,而2例可控性回肠造口术患者的14CO2呼出量增加。在4例可控性回肠造口术且维生素B12吸收不良的患者中,有证据表明存在淤滞性肠综合征,因为口服林可霉素治疗导致维生素B12吸收增加、粪便脂肪排泄减少以及回肠中拟杆菌浓度降低。