Berthoud S
Schweiz Med Wochenschr. 1979 Aug 25;109(32):1194-200.
Analysis of 2006 prescriptions given to 641 unselected patients by 360 doctors in the French- and Italian-speaking parts of Switzerland provides a wealth of information on prescription trends and the cost of medicine. The patients ordinarily received medication belonging to several therapeutic groups, usually 2 or 3 but up to 9 different groups. Each prescription averaged 2.08 drugs with a mean cost of 18.90 Swiss francs. The price varied considerably according to the group of drugs. Those related to the cardiovascular system were the most expensive closely followed by antibiotics, while the ophthalmological prescriptions were the least expensive. Hydergine is the most-sold drug in Switzerland, followed by Bactrim; however, if the various benzodiazepines were grouped together their sale would exceed the others. There are 62 different drugs for rheumatic conditions and 47 penicillins in Switzerland. The abundance of drugs and the prescription of medication with dubious action contribute to the inflationary cost of illness. For any given drug there is a striking parallelism between the number of pages publicizing it in 4 medical journals and total sales. This clearly demonstrates the influence of advertising on prescription trends. Doctors should be aware of this fact and rely on more objective sources of their information about drugs.
对瑞士法语区和意大利语区的360名医生为641名未经挑选的患者开具的2006份处方进行分析,可提供有关处方趋势和药品成本的丰富信息。患者通常会接受属于几个治疗组的药物,通常为2或3组,但最多可达9个不同组。每份处方平均有2.08种药物,平均成本为18.90瑞士法郎。价格因药物组而异。与心血管系统相关的药物最贵,其次是抗生素,而眼科处方最便宜。氢化麦角碱是瑞士销量最大的药物,其次是复方新诺明;然而,如果将各种苯二氮䓬类药物归为一组,它们的销量将超过其他药物。瑞士有62种不同的抗风湿药物和47种青霉素。药物种类繁多以及开具作用存疑的药物导致了疾病成本的上涨。对于任何一种给定的药物,其在4种医学期刊上宣传的页数与总销量之间存在显著的平行关系。这清楚地表明了广告对处方趋势的影响。医生应该意识到这一事实,并依靠更客观的药物信息来源。