Haase G M, Luce J M, Lock J P, Hammond W S, Penn I
Surgery. 1979 Nov;86(5):694-7.
A patient with primary hyperparathyroidism underwent cervical exploration and hemithyroidectomy. Only one normal parthyroid gland was found and was removed. Hypercalcemia persisted and subsequent arteriography localized a large mediastinal adenoma which was excised. Parathyroid autotransplantation of a small part of this tissue was performed and the patient was well for over a year. He again became markedly hypercalcemic and graft-dependent elevation of parathromone levels was demonstrated. Autograft resection resulted in normocalcemia. Nineteen months later hypercalcemia and elevated parathormone levels prompted re-exploration of the graft site and another enlarged implant was removed. This restored normocalcemia and normal parathromone levels. Parathyroid adenomatous tissue has the potential for autonomous hyperfunction, and caution must be exercised in its use in autotransplantation.
一名原发性甲状旁腺功能亢进患者接受了颈部探查和甲状腺半切除术。仅发现并切除了一个正常甲状旁腺。高钙血症持续存在，随后的动脉造影定位到一个大的纵隔腺瘤并将其切除。对该组织的一小部分进行了甲状旁腺自体移植，患者病情好转超过一年。他再次出现明显的高钙血症，并且证实甲状旁腺激素水平因移植而升高。自体移植切除后血钙恢复正常。19个月后，高钙血症和甲状旁腺激素水平升高促使对移植部位再次进行探查，又切除了一个增大的移植物。这恢复了血钙正常和甲状旁腺激素水平正常。甲状旁腺腺瘤组织有自主功能亢进的可能性，在自体移植中使用时必须谨慎。
