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慢性酒精中毒所致脑损伤的临床、心理测量及放射学征象

Clinical, psychometric and radiological signs of brain damage in chronic alcoholism.

作者信息

Carlsson C, Claeson L E, Karlsson K I, Pettersson L E

出版信息

Acta Neurol Scand. 1979 Aug;60(2):85-92. doi: 10.1111/j.1600-0404.1979.tb02955.x.

DOI:10.1111/j.1600-0404.1979.tb02955.x
PMID:495046
Abstract

A total of 34 male inpatients with advanced chronic alcoholism and a clinical picture of impaired working capacity were examined by pneumoencephalography and 29 of them by psychometric tests. All or almost all (depending on the criteria chosen) showed degenerative changes in the cerebrum and about one-third showed degenerative changes in the cerebellum. All 29 patients who were psychometrically investigated showed signs of cerebral dysfunction. The correlation between the single pneumoencephalographic and psychometric variables was at most 0.46 and abnormalities of the third ventricle showed the highest correlation to the psychometric variables. An overall assessment of the degree of degenerative changes in the cerebrum (pneumoencephalographic findings) and the degree of cerebral dysfunction (psychometric findings) resulted in a correlation of r = 0.54 (P less than 0.001).

摘要

对34名患有晚期慢性酒精中毒且有工作能力受损临床表现的男性住院患者进行了气脑造影检查,其中29名患者还接受了心理测试。所有患者或几乎所有患者(取决于所选标准)均显示大脑有退行性变化,约三分之一的患者小脑有退行性变化。接受心理测试的29名患者均显示出大脑功能障碍的迹象。单个气脑造影变量与心理测试变量之间的相关性最高为0.46,第三脑室异常与心理测试变量的相关性最高。对大脑退行性变化程度(气脑造影检查结果)和大脑功能障碍程度(心理测试结果)的总体评估得出相关性r = 0.54(P小于0.001)。

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[Is the increase in brain volume of abstinent alcoholics a sequela of rehydration?].
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