Rinieris P M, Stefanis C N, Lykouras E P, Varsou E K
Acta Psychiatr Scand. 1979 Sep;60(3):272-8. doi: 10.1111/j.1600-0447.1979.tb00275.x.
Results of the present study provide evidence of: 1) a positive association between bipolar affective disorder and blood type O and a corresponding negative association between the former and blood type A, 2) a positive association between unipolar affective disorder and blood type O, and 3) a positive association between involutional depression and blood type A and a corresponding negative association between the former and blood types B and O. Sex does not appear to modify the ABO blood types' distribution in patients with bipolar, unipolar affective disorder, or involutional depression, and the same holds for early- or late-onset of the illness in patients with bipolar or unipolar affective disorders. Findings in the present study do not support the validity of the bipolar-unipolar distinction of affective disorders, and provide evidence in favour of the view that involutional depression is a genetically distinct nosological entity.
1）双相情感障碍与O型血呈正相关，与A型血呈负相关；2）单相情感障碍与O型血呈正相关；3）更年期抑郁与A型血呈正相关，与B型血和O型血呈负相关。性别似乎不会改变双相情感障碍、单相情感障碍或更年期抑郁患者的ABO血型分布，双相情感障碍或单相情感障碍患者的疾病早发或晚发情况也是如此。本研究结果不支持情感障碍双相-单相区分的有效性，并为更年期抑郁是一种基因上独特的疾病实体这一观点提供了证据。
