Roepke J L, Kirksey A
Am J Clin Nutr. 1979 Nov;32(11):2249-56. doi: 10.1093/ajcn/32.11.2249.
Vitamin B6 nutriture was assessed during pregnancy and lactation to determine possible relationships among vitamin B6 intake, levels of the vitamin in biological fluids and the condition of the infant at birth. Vitamin B6 levels were measured in maternal serum and in urine at 5 and 7 months gestation and at delivery, in cord serum and in milk at 3 and 14 days postpartum. Intake of vitamin B6, less than the Recommended Dietary Allowances (1974) for pregnancy and lactation, 2.5 mg/day, resulted in lower levels of the vitamin in maternal serum at delivery and in cord serum than higher intakes. Mothers whose infants had unsatisfactory Apgar scores at 1 min, (less than 7) had significantly low intakes of vitamin B6 and lower levels of the vitamin in both serum and milk than mothers whose infants had satisfactory scores, (greater than or equal to 7). At 5 months gestation, levels of vitamin B6 in maternal serum were significantly correlated with levels of the vitamin in cord serum and in milk at 14 days postpartum. This stage of gestation precedes the period of rapid growth of the central nervous system of the fetus, and is, therefore, a critical time for the assessment of maternal vitamin B6 nutriture.
在孕期和哺乳期对维生素B6营养状况进行了评估，以确定维生素B6摄入量、生物体液中该维生素水平与婴儿出生时状况之间的可能关系。在妊娠5个月和7个月时以及分娩时测量了母血和尿液中的维生素B6水平，在产后3天和14天测量了脐血和乳汁中的维生素B6水平。维生素B6摄入量低于孕期和哺乳期的推荐膳食供给量（1974年）（2.5毫克/天），导致分娩时母血和脐血中该维生素水平低于较高摄入量时的水平。与婴儿阿氏评分满意（大于或等于7）的母亲相比，其婴儿在1分钟时阿氏评分不满意（低于7）的母亲维生素B6摄入量显著较低，血清和乳汁中该维生素水平也较低。在妊娠5个月时，母血中维生素B6水平与产后14天脐血和乳汁中该维生素水平显著相关。这个妊娠阶段先于胎儿中枢神经系统快速生长的时期，因此是评估母体维生素B6营养状况的关键时期。
