Graham G G, Morales E, Placko R P, MacLean W C
Am J Clin Nutr. 1979 Nov;32(11):2362-6. doi: 10.1093/ajcn/32.11.2362.
A precooked, instantized mixture of brown and black beans, with and without 0.3% DL-methione added, served as the only source of protein in the diets of 10 recovered malnourished infants and children 10 to 42 months of age. At 6.4 to 5.7% dietary protein calories stool wet weights were twice as high, apparent N absorption significantly lower (65.6 +/- 5.9 versus 87.5 +/- 2.3% of intake), and apparent N retention much lower (9.8 +/- 6.1 versus 34.5 +/- 10.2% of intake) than during preceding and following isocaloric and isonitrogenous casein-based diets. The addition of methionine resulted in minimal improvement in N retention and a highly suggestive increase in fasting plasma free methionine. Prolonged feeding of the methionine-enriched beans at 8.0 to 10.9% protein calories supported satisfactory growth and serum albumin levels in two of three children, not so in the smallest one, in whom repeated balance studies demonstrated no decrease over time in stool wet weight and on marginal improvement in N absorption and retention. The poor digestibility of the protein in these beans is the first-limiting factor in its utilization by infants and small children.
一种预先煮熟、速溶的黑豆和黑芸豆混合物,添加和未添加0.3%的DL-蛋氨酸,作为10名10至42个月大已康复的营养不良婴幼儿饮食中唯一的蛋白质来源。在饮食蛋白质热量为6.4%至5.7%时,粪便湿重是之前和之后等热量、等氮量的酪蛋白饮食期间的两倍,表观氮吸收率显著降低(分别为摄入量的65.6±5.9%和87.5±2.3%),表观氮潴留也低得多(分别为摄入量的9.8±6.1%和34.5±10.2%)。添加蛋氨酸使氮潴留仅有极小改善,且空腹血浆游离蛋氨酸有显著升高。在蛋白质热量为8.0%至10.9%的情况下,长期喂食富含蛋氨酸的豆类,三名儿童中有两名生长和血清白蛋白水平令人满意,最小的儿童则不然,在该儿童中反复进行的平衡研究表明,粪便湿重没有随时间下降,氮吸收和潴留仅有轻微改善。这些豆类中蛋白质的低消化率是婴幼儿利用其蛋白质的首要限制因素。