Davison P F
Science. 1966 Apr 22;152(3721):509-12. doi: 10.1126/science.152.3721.509.
Denatured DNA preparations from Escherichia coli were centrifuged to equilibrium in cesium chloride solutions. Hybridizing experiments with radioactively labeled ribosomal RNA showed that the DNA strands complementary to ribosomal RNA were distributed on the heavy side of the DNA band. By fractionating this band the DNA strands coding for ribosomal RNA may be enriched 5- to 20- fold.
将来自大肠杆菌的变性DNA制剂在氯化铯溶液中离心至平衡。用放射性标记的核糖体RNA进行的杂交实验表明，与核糖体RNA互补的DNA链分布在DNA带的重侧。通过对该带进行分级分离，编码核糖体RNA的DNA链可富集5至20倍。
