Strassner H T, Platt L D, Whittle M, Hill L M, Yeh S Y, Manning F A, Golde S H
Am J Obstet Gynecol. 1979 Nov 15;135(6):804-8. doi: 10.1016/0002-9378(79)90395-8.
The fetal biparietal diameter (BPD) was measured at the time of real-time ultrasound-directed amniocentesis in 159 cases and a phospholipid profile was obtained from the amniotic fluid. BPD measurements of 9.0, 8.7, and 9.2 cm were then compared with a lecithin/sphingomyelin (L/S) ratio greater than or equal to 2.0 for the ability to predict the presence of phosphatidylglycerol (PG) in the profile. The data from the diabetic and nondiabetic patients were analyzed separately. The results demonstrated that in the presence of a L/S ratio greater than or equal to 2.0 the BPD does not aid in the identification of amniotic fluid samples which contain PG in either the diabetic or nondiabetic groups. The data also confirmed previous findings that the BPD is not a reliable predictor of the L/S ratio. It is concluded that for the detection of PG in amniotic fluid, the use of real-time ultrasonic cephalometry cannot substitute for the performance of the phospholipid profile.
在159例实时超声引导羊膜腔穿刺时测量胎儿双顶径（BPD），并从羊水获得磷脂谱。然后将9.0、8.7和9.2厘米的BPD测量值与卵磷脂/鞘磷脂（L/S）比值大于或等于2.0进行比较，以预测磷脂谱中磷脂酰甘油（PG）的存在情况。分别分析糖尿病患者和非糖尿病患者的数据。结果表明，在L/S比值大于或等于2.0的情况下，BPD无助于识别糖尿病组或非糖尿病组中含有PG的羊水样本。数据还证实了先前的发现，即BPD不是L/S比值的可靠预测指标。结论是，对于羊水PG的检测，实时超声头颅测量不能替代磷脂谱检查。
