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关于不完全抗-Rh抗体的效价

On the valency of incomplete anti-Rh antibodies.

作者信息

Mandy J, Holmdahl I L, Lebis F B, Fudenberg H H

出版信息

Clin Exp Immunol. 1966 Jan;1(1):25-32.

Abstract

The univalency concept of the mechanism responsible for the failure of incomplete antibodies to produce direct agglutination of appropriate untreated red cells has been investigated. Artificially produced univalent (hybrid) 7S antibodies were found to differ in serologic behaviour from incomplete anti-Rh antibodies of the same molecular size. The data suggest that the so-called `univalent' anti-Rh antibody molecule is bivalent.

摘要

关于不完全抗体不能使适当的未经处理的红细胞产生直接凝集的机制的单价概念已被研究。人工制备的单价(杂交)7S抗体在血清学行为上与相同分子大小的不完全抗Rh抗体不同。数据表明,所谓的“单价”抗Rh抗体分子是二价的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7565/1579170/4f4df95f254a/clinexpimmunol00360-0030-a.jpg

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