细菌内毒素之间的杂交形成。
Hybrid formation between bacterial endotoxins.
作者信息
Rudbach J A, Milner K C, Ribi E
出版信息
J Exp Med. 1967 Jul 1;126(1):63-79. doi: 10.1084/jem.126.1.63.
Abstract
When endotoxins extracted from enteric bacteria were mixed in the presence of sodium deoxycholate, and the bile salt was subsequently removed by dialysis or by extraction with ethanol, a new type of endotoxin was formed. The latter material was as biologically active as the original endotoxins and possessed a combination of antigenic determinants that were previously unique to each of the individual endotoxins in the mixture. This hybrid formation between endotoxins was detected by immunodiffusion and radioautography and by quantitative precipitation procedures.
摘要
当从肠道细菌中提取的内毒素在脱氧胆酸钠存在的情况下混合，随后通过透析或用乙醇萃取去除胆汁盐时，会形成一种新型内毒素。后一种物质与原始内毒素具有相同的生物活性，并具有混合物中每种单独内毒素以前特有的抗原决定簇组合。通过免疫扩散、放射自显影和定量沉淀程序检测到内毒素之间的这种杂交形成。
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1
The preparation and properties of a specific polysaccharide from Bact. typhosum Ty(2): With an addendum by J. St L. Philpot, From the Department of Biochemistry, Oxford.来自牛津大学生物化学系的：鼠伤寒杆菌Ty(2)中一种特定多糖的制备及性质：附J. St L. Philpot的补遗
Biochem J. 1942 Apr;36(3-4):340-56. doi: 10.1042/bj0360340.
2
The formation of hybrid DNA molecules and their use in studies of DNA homologies.杂交DNA分子的形成及其在DNA同源性研究中的应用。
J Mol Biol. 1961 Oct;3:595-617. doi: 10.1016/s0022-2836(61)80024-7.
3
Preparation and host-reactive properties of endotoxin with low content of nitrogen and lipid.低氮和脂质含量内毒素的制备及其宿主反应特性
J Exp Med. 1961 Nov 1;114(5):647-63. doi: 10.1084/jem.114.5.647.
4
The occurrence of cell wall constituents in stable Proteus L forms.细胞壁成分在稳定变形杆菌L型中的出现。
Acta Pathol Microbiol Scand. 1962;55:475-82. doi: 10.1111/j.1699-0463.1962.tb04153.x.
5
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7
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9
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