DeMeester T R, Golomb H M, Kirchner P, Rezai-Zadeh K, Bitran J D, Streeter D L, Hoffman P C, Cooper M
Ann Thorac Surg. 1979 Nov;28(5):451-64. doi: 10.1016/s0003-4975(10)63155-4.
Gallium-67 scanning was evaluated in 100 patients with proved carcinoma of the lung. It was valuable in separating primary from secondary lung tumors, determining the extent of contralateral hilar or mediastinal lymph node involvement, and detecting distant organ metastases. In addition to multiplane whole-body Ga-67 tomographic scanning, colloid liver scans, bone scans, and computerized axial tomography scans of the brain were obtained to determine the presence of distant metastasis. The gallium scan detected 11 of 12 occult metastases and identified 7 of 7 liver, 9 of 14 brain, 4 of 4 soft tissues, 1 of 4 contralateral lung, and 9 of 11 bone metastases. The whole-body gallium scan accurately detected or excluded extrathoracic metastatic disease in 11 of 12 patients examined postmortem within three months of a gallium scan. An approach is recommended using gallium scanning along with chest roentgenograms for clinical staging and preoperative evaluation of patients with carcinoma of the lung. Specific organ scans should be reserved for the occasional symptomatic patient with a negative gallium scan or for clarification of an indeterminate gallium scan.
对100例已证实患有肺癌的患者进行了镓-67扫描评估。它在区分原发性和继发性肺肿瘤、确定对侧肺门或纵隔淋巴结受累程度以及检测远处器官转移方面具有重要价值。除了多平面全身镓-67断层扫描外，还进行了胶体肝扫描、骨扫描和脑部计算机断层扫描，以确定是否存在远处转移。镓扫描检测出12例隐匿性转移中的11例，并识别出7例肝脏转移中的7例、14例脑转移中的9例、4例软组织转移中的4例、4例对侧肺转移中的1例以及11例骨转移中的9例。在镓扫描后三个月内进行尸检的12例患者中，全身镓扫描准确检测或排除了胸外转移性疾病的有11例。建议采用镓扫描结合胸部X线片的方法对肺癌患者进行临床分期和术前评估。对于镓扫描阴性的偶发有症状患者或为了明确不确定的镓扫描结果，应保留特定器官扫描。
