Re M, Carpino F, Familiari G, Iannitelli M, Vicari A
Arch Androl. 1979 Jun;2(4):283-9. doi: 10.3109/01485017908987327.
Previous studies on some cases of idiopathic spermatidic arrest showed an anomaly in glucose metabolism, in particular decreased utilization of glycogen at stage 3 of spermatogenesis, when condensation of the spermatid head commences. Histological patterns seen on light microscopy confirmed the reduced utilization of glycogen at stage 3 of spermatogenesis. Electron microscopy revealed an arrest at stage 3 of spermiogenesis and, at the cytoplasm level of the Sertoli cell, a modification in the smooth endoplasmic reticulum characterized by the presence of dilated cisternae. From a morphological viewpoint, the equivalent of a biochemical modification which characterizes this maturation disorder in the germinal epithelium is hypothesized.
先前对一些特发性精子发生停滞病例的研究显示，葡萄糖代谢存在异常，特别是在精子发生的第3阶段，即精子头部开始凝聚时，糖原利用减少。光镜下观察到的组织学模式证实了精子发生第3阶段糖原利用减少。电子显微镜显示精子形成停滞在第3阶段，在支持细胞的细胞质水平，滑面内质网出现改变，其特征为有扩张的池。从形态学观点推测，生精上皮中这种成熟障碍所特有的生化改变具有同等表现。
