Eckert H, Wildner G P
Arch Geschwulstforsch. 1979;49(4):305-10.
Experiences with a prescreening test for tumor cells in cytological material (pleural effusions, ascites) are reported. With the aid of alkaline phosphatase positive reacting tumor cells in smears (pleural fluid, ascites) are easily detectable. This test gives a positive result in 65% of patients with different organ tumors whereas with routine cytology tumor cells were found in 72% of this patients. Among different organ tumors highest percentage of positive phosphatase tests are found by bronchial, gastric and ovarial carcinomas (3/4 of cases), to a less degree bycarcinoma of the breast and others (1/2 of cases). All together phosphatase test is positive in 90% of all effusions, containing cytologically diagnosed tumor cells. The adventages, disadventages and the usefullness of this method as a prescreening test are discussed.
报告了对细胞学材料（胸腔积液、腹水）中肿瘤细胞进行预筛查试验的经验。借助碱性磷酸酶，涂片（胸水、腹水）中反应阳性的肿瘤细胞易于检测到。该试验在65%的不同器官肿瘤患者中呈阳性结果，而常规细胞学检查在这些患者中的肿瘤细胞检出率为72%。在不同器官肿瘤中，支气管癌、胃癌和卵巢癌的磷酸酶试验阳性率最高（3/4的病例），乳腺癌和其他癌症的阳性率较低（1/2的病例）。总体而言，在所有经细胞学诊断含有肿瘤细胞的积液中，磷酸酶试验的阳性率为90%。讨论了该方法作为预筛查试验的优点、缺点和实用性。
