Shapovalov Iu N, Barsukov N P
Arkh Anat Gistol Embriol. 1979 Sep;77(9):25-33.
The structure of the presomite human embryo was investigated at embryogenesis. The embryonic shield is a three-layer gastrula 810 mkm long in the anteroposterior direction and 855 mkm wide (at the level of the primitive nodule). The primitive streak is 200 mkm long; the primitive nodule is well pronounced. All three germ layers are separately followed only in the cranial end of the embryo. The chordo-mesodermal process, 80 mkm long, is seen and is situated anterior to the primitive nodule, between ecto- and endoderm; in its zone, as well as in the area of the primary nodule and the primary streak, along the middle line, the germ layers are in close contact with each other. In the caudal end the mesoderm grows thin, and the external and internal layers come into contact forming the cloacal membrane. Extraembryonic formations are described: amniotic vesicle, yolk sac, amniotic peduncle, allantois and chorionic membrane wall. Together with the extraembryonic ecto- and endoderm, exocoelomic mesoderm participates in the formation of walls of the primitive germ vesicles. The yolk sac wall contains blood islets. Primary blood vessels are detected in the connective tissue matrix of the chorionic layer and in the amniotic peduncle. According to the anamnesis, morphological data and comparing to the data of the literature on presomitic human embryos, the age of the embryo "Krym" is determined as old as 17 days.
在胚胎发生过程中对原肠胚期人类胚胎的结构进行了研究。胚胎盾是一个三层原肠胚,前后方向长810微米,宽855微米(在原结水平)。原条长200微米;原结清晰可见。仅在胚胎的头端能分别追踪到所有三个胚层。可见到长80微米的脊索中胚层突起,它位于原结前方,在外胚层和内胚层之间;在其区域以及原结和原条区域,沿着中线,胚层彼此紧密接触。在尾端,中胚层变薄,外层和内层接触形成泄殖腔膜。描述了胚外结构:羊膜囊、卵黄囊、羊膜蒂、尿囊和绒毛膜壁。胚外中胚层与胚外外胚层和内胚层一起参与原始胚泡壁的形成。卵黄囊壁含有血岛。在绒毛膜层的结缔组织基质和羊膜蒂中检测到初级血管。根据病史、形态学数据并与关于原肠胚期人类胚胎的文献数据进行比较,确定“克里米亚”胚胎的年龄为17天。