• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[On the biosynthesis of penicillin. Studies on the enzymatic activation of phenylacetic acid and phenoxyacetic acid as well as the formation of penicillin from 6-aminopenicillanic acid and activated side chain acids by mycelial homogenates and cell-free extracts of Penicillium chrysogenum].

作者信息

Brunner R, Röhr M, Zinner M

出版信息

Hoppe Seylers Z Physiol Chem. 1968 Jan;349(1):95-103. doi: 10.1515/bchm2.1968.349.1.95.

DOI:10.1515/bchm2.1968.349.1.95
PMID:4969964
Abstract
摘要

相似文献

1
[On the biosynthesis of penicillin. Studies on the enzymatic activation of phenylacetic acid and phenoxyacetic acid as well as the formation of penicillin from 6-aminopenicillanic acid and activated side chain acids by mycelial homogenates and cell-free extracts of Penicillium chrysogenum].[关于青霉素的生物合成。产黄青霉菌丝体匀浆和无细胞提取物对苯乙酸和苯氧乙酸的酶促活化以及由6-氨基青霉烷酸和活化侧链酸形成青霉素的研究]
Hoppe Seylers Z Physiol Chem. 1968 Jan;349(1):95-103. doi: 10.1515/bchm2.1968.349.1.95.
2
Design of an enzymatic hybrid system: a useful strategy for the biosynthesis of benzylpenicillin in vitro.酶促杂交系统的设计：体外生物合成苄青霉素的有效策略。
FEMS Microbiol Lett. 1990 Oct;60(1-2):113-6. doi: 10.1111/j.1574-6968.1990.tb03872.x.
3
Penicillin acyltransferase in Penicillium chrysogenum.产黄青霉中的青霉素酰基转移酶。
J Bacteriol. 1967 Nov;94(5):1502-8. doi: 10.1128/jb.94.5.1502-1508.1967.
4
Specificity of penicillin acylase of Fusarium and of Penicillium chrysogenum.镰刀菌和产黄青霉青霉素酰化酶的特异性
Appl Microbiol. 1968 Oct;16(10):1557-63. doi: 10.1128/am.16.10.1557-1563.1968.
5
Utilization of side-chain precursors for penicillin biosynthesis in a high-producing strain of Penicillium chrysogenum.在产黄青霉高产菌株中利用侧链前体进行青霉素生物合成。
Appl Microbiol Biotechnol. 1994 Feb;40(6):883-7. doi: 10.1007/BF00173993.
6
Uptake of phenylacetic acid by Penicillium chrysogenum Wis 54-1255: a critical regulatory point in benzylpenicillin biosynthesis.产黄青霉Wis 54-1255对苯乙酸的摄取：苄青霉素生物合成中的一个关键调控点。
J Antibiot (Tokyo). 1989 Sep;42(9):1398-409. doi: 10.7164/antibiotics.42.1398.
7
Amplification and disruption of the phenylacetyl-CoA ligase gene of Penicillium chrysogenum encoding an aryl-capping enzyme that supplies phenylacetic acid to the isopenicillin N-acyltransferase.产黄青霉苯乙酰辅酶A连接酶基因的扩增与破坏，该基因编码一种为异青霉素N-酰基转移酶提供苯乙酸的芳基封端酶。
Biochem J. 2006 Apr 1;395(1):147-55. doi: 10.1042/BJ20051599.
8
Penicillin productivity and glutathione-dependent detoxification of phenylacetic and phenoxyacetic acids in Penicillium chrysogenum.产黄青霉中青霉素的产量以及苯乙酸和苯氧乙酸的谷胱甘肽依赖性解毒作用
J Basic Microbiol. 2001;41(2):67-73. doi: 10.1002/1521-4028(200105)41:2<67::AID-JOBM67>3.0.CO;2-J.
9
Biosynthesis of benzylpenicillin (G), phenoxymethylpenicillin (V) and octanoylpenicillin (K) from glutathione S-derivatives.由谷胱甘肽 S-衍生物生物合成苄青霉素（G）、苯氧甲基青霉素（V）和辛酰青霉素（K）。
J Antibiot (Tokyo). 1990 Jun;43(6):684-91. doi: 10.7164/antibiotics.43.684.
10
Catabolism of phenylacetic acid in Penicillium rubens. Proteome-wide analysis in response to the benzylpenicillin side chain precursor.红色红曲霉中苯乙酸的分解代谢。对苯青霉素侧链前体响应的蛋白质组全分析。
J Proteomics. 2018 Sep 15;187:243-259. doi: 10.1016/j.jprot.2018.08.006. Epub 2018 Aug 6.

引用本文的文献

1
Molecular regulation of beta-lactam biosynthesis in filamentous fungi.丝状真菌中β-内酰胺生物合成的分子调控
Microbiol Mol Biol Rev. 1998 Sep;62(3):547-85. doi: 10.1128/MMBR.62.3.547-585.1998.
2
Uptake of phenoxyacetic acid by Penicillium chrysogenum.产黄青霉对苯氧乙酸的摄取
Appl Microbiol Biotechnol. 1995 Mar;42(6):945-50. doi: 10.1007/BF00191195.
3
Utilization of side-chain precursors for penicillin biosynthesis in a high-producing strain of Penicillium chrysogenum.在产黄青霉高产菌株中利用侧链前体进行青霉素生物合成。
Appl Microbiol Biotechnol. 1994 Feb;40(6):883-7. doi: 10.1007/BF00173993.
4
Specificity of penicillin acylase of Fusarium and of Penicillium chrysogenum.镰刀菌和产黄青霉青霉素酰化酶的特异性
Appl Microbiol. 1968 Oct;16(10):1557-63. doi: 10.1128/am.16.10.1557-1563.1968.
5
Purification to homogeneity and characterization of acyl coenzyme A:6-aminopenicillanic acid acyltransferase of Penicillium chrysogenum.产黄青霉酰基辅酶A：6-氨基青霉烷酸酰基转移酶的纯化至均一性及特性鉴定
Antimicrob Agents Chemother. 1987 Nov;31(11):1675-82. doi: 10.1128/AAC.31.11.1675.
6
Behaviour of tritium-labelled isopenicillin N and 6-aminopenicillanic acid as potential penicillin precursors in an extract of Penicillum chrysogenum.氚标记的异青霉素N和6-氨基青霉烷酸作为产黄青霉提取物中潜在青霉素前体的行为。
Biochem J. 1975 Dec;151(3):741-6. doi: 10.1042/bj1510741.
7
Biosynthesis of aflatoxins.黄曲霉毒素的生物合成
Bacteriol Rev. 1977 Dec;41(4):822-55. doi: 10.1128/br.41.4.822-855.1977.