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流产布鲁氏菌生物型5感染的诊断与治疗

Diagnosis and treatment of infection with Brucella abortus, biotype 5.

作者信息

Robertson L

出版信息

J Clin Pathol. 1967 Mar;20(2):199-203. doi: 10.1136/jcp.20.2.199.

Abstract

A case of brucellosis due to Brucella abortus, biotype 5, occurred in a bulk milk-tanker driver who collected milk from refrigerated tanks on 23 farms. The organism was isolated from blood cultures by using a serum dextrose broth containing antibiotics. Serological investigations indicate that both abortus and melitensis antigen suspensions should be used in the investigation of cases of suspected brucellosis. As Brucella abortus is an intracellular parasite heavy, prolonged, antibiotic therapy is necessary in the treatment of the disease. The danger of inadequate treatment of the acute disease is that it may become chronic, and response to antibiotic therapy in chronic brucellosis is not good.

摘要

一名散装奶罐车司机感染了生物型5流产布鲁氏菌引起的布鲁氏菌病,该司机从23个农场的冷藏罐中收集牛奶。通过使用含抗生素的血清葡萄糖肉汤从血培养物中分离出该病原体。血清学调查表明,在疑似布鲁氏菌病病例的调查中应同时使用流产布鲁氏菌和马尔他布鲁氏菌抗原悬液。由于流产布鲁氏菌是一种胞内寄生菌,因此在治疗该疾病时需要进行长期、大量的抗生素治疗。急性病治疗不充分的风险在于可能会转为慢性病,而慢性布鲁氏菌病对抗生素治疗的反应不佳。

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