Balitskiĭ K P, Syromiatnikov A V
Biull Eksp Biol Med. 1979 Oct;88(10):447-50.
Acute experiments on rats showed that the intragastric administration of an aqueous solution of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) elicited depression of the electrical activity of the gastric wall manifested by a decrease in the amplitude and frequency of the basic electrical rhythm and by its complete stopping in most cases. MNNG abolished the excitatory reaction caused both by the vagal electric stimulation and administration of carbacholine, but there persists an inhibitory reaction elicited both by the vagal stimulation and infusion of ATP.
对大鼠进行的急性实验表明，胃内给予N-甲基-N'-硝基-N-亚硝基胍（MNNG）水溶液会导致胃壁电活动抑制，表现为基本电节律的幅度和频率降低，且在大多数情况下完全停止。MNNG消除了迷走神经电刺激和给予卡巴胆碱所引起的兴奋反应，但迷走神经刺激和输注ATP所引起的抑制反应仍然存在。
