Puigbó J J, Nava Rhode J R, Carcía Barrios H, Gil Yépez C
Bull World Health Organ. 1968;39(3):341-8.
The paper reports on a 4-year follow-up study that represents the continuation of a previous cross-sectional study on Chagas' disease carried out in a rural community (Belén) in Venezuela. The earlier study included 1210 persons all over 5 years of age out of a total of 1656 inhabitants and demonstrated a high prevalence of Chagas' infection (47.3%) and a high rate of Chagas' disease seropositivity among those with chronic myocardial heart disease (84.8%); heart disease was found in 17.3% of persons studied. The follow-up study was based on 812 persons and established that in the sample the frequency of Chagas' infection was 16.3% and that of heart disease 2.2%. Clinical, electrocardiographic and radiological analyses were made on patients with previous heart disease as well as on new patients. Different evolutive electrocardiographic patterns have been found, including variations ranging from normal to definitively abnormal.
该论文报道了一项为期4年的随访研究，该研究是之前在委内瑞拉一个农村社区（贝伦）开展的关于恰加斯病横断面研究的延续。早期研究涵盖了1656名居民中所有5岁以上的1210人，结果显示恰加斯感染的患病率很高（47.3%），在患有慢性心肌心脏病的人群中恰加斯病血清阳性率很高（84.8%）；在接受研究的人群中，17.3%的人患有心脏病。随访研究基于812人进行，并确定在样本中恰加斯感染的频率为16.3%，心脏病的频率为2.2%。对既往患有心脏病的患者以及新患者进行了临床、心电图和放射学分析。发现了不同的心电图演变模式，包括从正常到明显异常的各种变化。
