感染鸡瘟病毒的鸡胚细胞中的核糖核酸合成
Ribonucleic acid synthesis in chick embryo cells infected with fowl-plague virus.
作者信息
Skehel J J, Burke D C
出版信息
J Virol. 1969 Apr;3(4):429-38. doi: 10.1128/JVI.3.4.429-438.1969.
Abstract
Increases in ribonucleic acid (RNA) polymerase activity were detected in both the nuclear and ribosomal fractions of chick embryo cells infected with fowl-plague virus. These were observed only in the presence of all four nucleoside triphosphates and were not affected by actinomycin D. The RNA polymerase activity of the ribosomal fraction was shown to be associated with a component of infected cells of sedimentation coefficient approximately 70S. This component also contained infected cell-specific RNA and protein molecules.
摘要
在感染了禽瘟病毒的鸡胚细胞的细胞核和核糖体组分中均检测到核糖核酸（RNA）聚合酶活性增加。这些增加仅在所有四种核苷三磷酸存在的情况下才被观察到，并且不受放线菌素D的影响。核糖体组分的RNA聚合酶活性与沉降系数约为70S的感染细胞成分相关。该成分还包含感染细胞特异性的RNA和蛋白质分子。
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