Herschorn S, Hardy B E, Churchill B M
Can J Surg. 1979 Sep;22(5):412-8.
The authors reviewed the records of eight children with renal cell carcinoma and correlated the clinical presentation, pathological and radiologic findings, stage and treatment of the disease with patient survival. Angiography revealed tumours of sparse neovascularity, associated with varied histologic patterns. Patient survival was dependent on the stage of the disease at the time of treatment; treatment of localized disease was effective but of metastatic disease was generally poor. Tumour staging appeared to be the only reliable indicator of prognosis. Children with renal cell carcinoma differ from adults in that a palpable mass in a child does not necessarily indicate that there is metastatic disease.
作者回顾了8例肾细胞癌患儿的病历，并将该疾病的临床表现、病理和放射学检查结果、分期及治疗与患者生存率进行了关联分析。血管造影显示肿瘤血管稀疏，伴有多种组织学类型。患者生存率取决于治疗时疾病的分期；局限性疾病的治疗有效，但转移性疾病的治疗效果通常较差。肿瘤分期似乎是唯一可靠的预后指标。儿童肾细胞癌与成人不同，儿童可触及肿块并不一定表明存在转移性疾病。
