Holmes I H, Doherty R L
J Virol. 1970 Jan;5(1):91-6. doi: 10.1128/JVI.5.1.91-96.1970.
The development of the virus of bovine ephemeral fever in mouse brain has been studied by electron microscopy. The virus particles are bullet-shaped, 70 by 145 nm, and slightly tapered toward the rounded end. The outer envelope is closely apposed to an electron-dense shell, about 12 nm thick, but no other internal structure is visible. The virus strains studied bud from the marginal membranes of neurones, but intracytoplasmic development, possibly aberrant, was also observed with one strain. Ephemeral fever virus is thus obviously a rhabdovirus, with points of resemblance to vesicular stomatitis, Flanders-Hart Park, and Kern Canyon viruses on the one hand, and to rabies virus on the other, but is structurally distinct from any of these.
通过电子显微镜对牛流行热病毒在小鼠脑中的发育进行了研究。病毒粒子呈子弹状，70×145纳米，向圆形末端略微变细。外膜紧密附着于一个约12纳米厚的电子致密壳，但未见其他内部结构。所研究的病毒株从神经元的边缘膜出芽，但也观察到一个病毒株有胞质内发育，可能是异常的。因此，流行热病毒显然是一种弹状病毒，一方面与水疱性口炎病毒、佛兰德斯-哈特帕克病毒和克恩峡谷病毒有相似之处，另一方面与狂犬病病毒有相似之处，但在结构上与这些病毒均不同。
