Waisman M, Schweppy I
Clin Orthop Relat Res. 1979 Jul-Aug(142):244-8.
Internal fixation with plate and screws was combined with administration of L-Dopa, which presumably operates by stimulating release of growth hormone. The combination induces osteogenesis, callus formation and complete union in the experimental femur osteotomy gap (10-20 mm long). Complete clinical and radiologic union was achieved in dogs treated for 3-6 weeks, thus achieving healing of a bone gap which otherwise would have formed a pseudarthrosis.
钢板螺钉内固定与左旋多巴联合应用，左旋多巴可能通过刺激生长激素释放起作用。这种联合可诱导实验性股骨截骨间隙（10 - 20毫米长）内的成骨、骨痂形成和完全愈合。接受治疗3 - 6周的犬实现了完全的临床和影像学愈合，从而治愈了原本会形成假关节的骨间隙。
