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The absorption, distribution, excretion, and biotransformation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in animals.

作者信息

Oliverio V T, Vietzke W M, Williams M K, Adamson R H

出版信息

Cancer Res. 1970 May;30(5):1330-7.

PMID:4987693
Abstract
摘要

相似文献

1
The absorption, distribution, excretion, and biotransformation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in animals.
Cancer Res. 1970 May;30(5):1330-7.
2
The uptake, distribution, and antitumor activity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in the murine glioma.
Cancer Res. 1970 Oct;30(10):2451-5.
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Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis.
Cancer Res. 1971 Mar;31(3):332-6.
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Nitrosoureas: 1,3-bis(2-chloroethyl)-1-nitrosourea (NSC-409962; BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC-79037; CCNU)--clinical brochure.
Cancer Chemother Rep 3. 1968 Dec;1(1):115-51.
5
Some effects of 1, 3-bis(2-chloroethyl)-1-nitrosourea upon the synthesis of protein and nucleic acids in vivo and in vitro.1,3-双(2-氯乙基)-1-亚硝基脲对体内和体外蛋白质及核酸合成的某些影响。
Cancer Res. 1965 Nov;25(10):1770-8.
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Effects of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) and its degradation products on progression of L1210 cells through the cell cycle.
Cancer Chemother Rep. 1971 Jun;55(3):215-20.
7
Interaction of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) with nucleic acids and proteins in vivo and in vitro.1-(2-氯乙基)-3-环己基-1-亚硝基脲(NSC 79037)在体内和体外与核酸及蛋白质的相互作用
Cancer Res. 1972 Jan;32(1):22-7.
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Comparative effects of the antitumor agents 5-(Dimethyltriazeno)-imidazole-4-carboxamide and 1,3-bis(2-chloroethyl)-1-nitrosourea on cell cycle of L1210 leukemia cells in vivo.抗肿瘤药物5-(二甲基三氮烯)-咪唑-4-甲酰胺和1,3-双(2-氯乙基)-1-亚硝基脲对L1210白血病细胞体内细胞周期的比较作用
Cancer Res. 1970 Aug;30(8):2173-90.
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Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds upon the synthesis of DNA by cell-free systems.
Cancer Res. 1968 Jan;28(1):52-9.
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Absorption, tissue distribution, and excretion of the anti-neoplastic agent guanazole in the rat.抗肿瘤药物胍唑在大鼠体内的吸收、组织分布及排泄
Res Commun Chem Pathol Pharmacol. 1974 Mar;7(3):497-512.

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Low apparent risk of CCNU (lomustine)-associated clinical hepatotoxicity in cats.猫中洛莫司汀(CCNU)相关临床肝毒性的表观风险较低。
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Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.静脉注射亚硝基脲后小鼠体内布拉顿 - 马歇尔阳性物质的分布情况。
Cancer Chemother Pharmacol. 1980;4(4):243-8. doi: 10.1007/BF00255268.
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The absorption, distribution and excretion of 3 H-chlorambucil in rats bearing the Yoshida ascites sarcoma.3H-苯丁酸氮芥在吉田腹水肉瘤大鼠体内的吸收、分布及排泄情况。
Br J Cancer. 1971 Dec;25(4):831-7. doi: 10.1038/bjc.1971.96.
8
Clinical pharmacokinetics of oral CCNU (lomustine).口服洛莫司汀(CCNU)的临床药代动力学
Cancer Chemother Pharmacol. 1985;14(2):125-31. doi: 10.1007/BF00434350.
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The hepatotoxicity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in rats. Ultrastructural evidence of a delayed microtubular toxicity.
Cancer Chemother Pharmacol. 1988;22(2):153-62. doi: 10.1007/BF00257314.
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Interference with effects of amphotericin B on Candida albicans cells by 2-chloroethyl-1-nitrosoureas.2-氯乙基-1-亚硝基脲对两性霉素B作用于白色念珠菌细胞效果的干扰
Antimicrob Agents Chemother. 1988 Mar;32(3):327-30. doi: 10.1128/AAC.32.3.327.