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吐温WR1339与脂肪酸的络合作用及其与结核分枝杆菌生长的关系

Complexing of fatty acids by Triton WR1339 in relation to growth of Mycobacterium tuberculosis.

作者信息

Hedgecock L W

出版信息

J Bacteriol. 1970 Aug;103(2):520-2. doi: 10.1128/jb.103.2.520-522.1970.

Abstract

Mycobacterium tuberculosis grew in the presence of toxic concentrations of free fatty acids when an adequate amount of triton WR1339 was added to the medium. Triton produced a solubilizing effect on turbid suspensions of fatty acids, indicating the formation of a detergent-lipid complex. Oleic acid complexed with triton served as a source of carbon for growth of M. tuberculosis.

摘要

当向培养基中添加足量的吐温WR1339时,结核分枝杆菌能在有毒浓度的游离脂肪酸存在的情况下生长。吐温对脂肪酸的浑浊悬浮液产生了增溶作用,表明形成了一种洗涤剂 - 脂质复合物。与吐温复合的油酸作为结核分枝杆菌生长的碳源。

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