Kreienbühl G, Gattiker R
Anaesthesist. 1976 Feb;25(2):47-50.
Hypocapnia during extracorporeal circulation in hypothermia increases oxygen consumption. Po2 in mixed venous blood decreases. This probably reflects a decrease in tissue oxygen tension. Hyperventilation will therefore increase the risk of hypoxia in critically perfused tissues. Therefore we recommend to keep PaCO2 (T) constant at 40 mm Hg during hypothermia.
低温体外循环期间的低碳酸血症会增加氧消耗。混合静脉血中的氧分压降低。这可能反映了组织氧张力的下降。因此,过度通气会增加灌注严重不足组织发生缺氧的风险。所以我们建议在低温期间将动脉血二氧化碳分压(体温校正后)维持在40mmHg不变。